Dr. Frank Hull, MD
Principal Investigator & Board-Certified Pulmonologist

Quick Credentials
- Board-Certified Pulmonologist
- Critical Care Medicine Specialist
- Sleep Medicine Expert
- 20+ Years Clinical Research
- Multiple FDA-Approved Treatments
- Published Research Author
Leading Respiratory Medicine Research in South Florida
Dr. Frank Hull is a board-certified pulmonologist and principal investigator at Lung Research Florida, where he leads groundbreaking clinical trials in respiratory medicine. With over two decades of experience in both clinical practice and research, Dr. Hull has been instrumental in developing breakthrough treatments that have improved the lives of millions of patients with COPD, asthma, bronchiectasis, and chronic cough.
Research Excellence
Principal investigator on 100+ clinical trials leading to multiple FDA-approved respiratory treatments
Clinical Expertise
Board-certified in Pulmonary Medicine, Critical Care, and Sleep Medicine
Innovation Leader
Pioneer in biologic therapy research and precision medicine approaches
Published Author
Extensive publications in leading medical journals and research contributions
Education & Professional Training
Comprehensive medical education and specialized training in respiratory medicine
Medical Degree
Doctor of Medicine (MD)
Graduated with honors from an accredited medical school with extensive training in internal medicine and respiratory physiology
Internal Medicine Residency
Internal Medicine Training Program
Comprehensive three-year residency training in internal medicine with focus on complex medical conditions and patient care
Pulmonary & Critical Care Fellowship
Advanced Specialty Training
Specialized fellowship training in pulmonary medicine and critical care, with emphasis on respiratory research and advanced therapies
Sleep Medicine Fellowship
Sleep Disorders Specialization
Additional fellowship training in sleep medicine, providing comprehensive care for sleep-related breathing disorders
Clinical Research Training
Good Clinical Practice Certification
Extensive training in clinical research methodology, FDA regulations, and ethical conduct of human subjects research
Board Certifications & Specializations
Multiple board certifications ensuring the highest standards of medical care
Pulmonary Medicine
American Board of Internal Medicine
Specialized certification in the diagnosis and treatment of respiratory diseases including asthma, COPD, and interstitial lung diseases
Critical Care Medicine
American Board of Internal Medicine
Advanced certification in intensive care medicine for critically ill patients with respiratory and multi-organ failure
Sleep Medicine
American Board of Sleep Medicine
Specialized certification in sleep disorders, sleep-related breathing disorders, and sleep apnea management
Clinical Research
Good Clinical Practice Certified
Certification in ethical conduct of clinical research, FDA regulations, and human subjects protection
Clinical Research Expertise
Over 20 years of pioneering research in respiratory medicine
Research Focus Areas
Dr. Hull's research career has spanned the evolution of respiratory medicine from traditional bronchodilators to today's cutting-edge biologic therapies. His work has been instrumental in bringing numerous breakthrough treatments from laboratory to patient bedside.
Severe Asthma Biologics
Pioneering research in anti-IL-5, anti-IL-4/IL-13, and anti-TSLP therapies
- Principal investigator on landmark biologic therapy trials
- Expert in biomarker-driven treatment selection
- Specialist in achieving clinical remission outcomes
- Leader in pediatric and adult severe asthma research
COPD Innovation
Advanced research in COPD exacerbation prevention and cardiovascular protection
- Novel anti-inflammatory approaches for COPD
- Cardiovascular risk reduction in COPD patients
- Biomarker identification for COPD phenotyping
- Disease modification and progression studies
Chronic Cough Breakthroughs
Leading investigator in P2X3 receptor antagonist development
- First-in-human studies of novel cough treatments
- Quality of life outcome research
- Objective cough monitoring technologies
- Neurogenic pathway modulation studies
Bronchiectasis Research
Innovative approaches to infection prevention and airway protection
- Anti-Pseudomonas bispecific antibody trials
- Exacerbation prevention strategies
- Novel anti-inflammatory approaches
- Airway clearance optimization studies
Research Impact & Achievements
Translating research into real-world improvements for patients worldwide
FDA Approvals
Principal investigator on clinical trials that led to multiple FDA-approved respiratory medications now helping millions of patients worldwide
Published Research
Extensive publication record in leading peer-reviewed medical journals including respiratory medicine and clinical research publications
Medical Education
Active involvement in training the next generation of pulmonologists and clinical researchers through mentorship and educational programs
Professional Leadership
Leadership roles in professional organizations and advisory positions for respiratory medicine research initiatives
Professional Memberships & Affiliations
Active participation in leading medical organizations
American Thoracic Society (ATS)
Active member and contributor to respiratory medicine research and guidelines
American College of Chest Physicians (ACCP)
Fellow and participant in pulmonary medicine education and research initiatives
American Academy of Sleep Medicine (AASM)
Member specializing in sleep-related breathing disorders and research
Association of Clinical Research Professionals (ACRP)
Professional member committed to excellence in clinical research practices
International Association for the Study of Pain (IASP)
Research member focusing on respiratory-related pain and cough hypersensitivity
Global Initiative for Chronic Obstructive Lung Disease (GOLD)
Contributor to COPD research guidelines and treatment recommendations
Clinical Philosophy & Approach
"My mission is to bridge the gap between cutting-edge scientific discoveries and real-world patient care. Every clinical trial we conduct is an opportunity to transform lives – not just for our participants, but for millions of patients worldwide who will benefit from the treatments we help develop." - Dr. Frank Hull
Patient-Centered Research
Every research decision is made with patient wellbeing and quality of life as the primary consideration
Scientific Excellence
Commitment to the highest standards of scientific rigor and ethical research practices
Innovation Focus
Pursuing breakthrough treatments that can achieve disease remission, not just symptom management
Collaborative Care
Working closely with referring physicians to ensure comprehensive, coordinated patient care

Current Research Initiatives (2025)
Leading tomorrow's breakthrough treatments today
Next-Generation Biologics
Investigating dual-pathway inhibitors and ultra-long-acting biologic therapies for severe asthma and COPD
- Anti-TSLP therapy expansion studies
- Twice-yearly biologic injection trials
- Clinical remission outcome research
Precision Medicine
Developing biomarker-driven treatment selection to optimize therapeutic outcomes for individual patients
- Genetic profiling for treatment response
- Inflammatory biomarker analysis
- Personalized dosing strategies
Digital Health Integration
Incorporating advanced monitoring technologies and AI-assisted outcome tracking in clinical trials
- Remote patient monitoring systems
- Digital biomarker development
- AI-powered symptom analysis
Disease Modification
Researching treatments that can fundamentally alter disease progression rather than just managing symptoms
- Airway remodeling prevention
- Immune system modulation
- Long-term disease course alteration
Work with Dr. Hull
Professional collaboration and patient referral opportunities