Available Clinical Trials

Currently showing 6 clinical trials

Currently Enrolling Trials

Now Enrolling

AIRLYMPUS Study: High-Risk Asthma

Testing Lunsekimig, which targets both IL-13 and TSLP pathways for patients with asthma and elevated T2 inflammation.

Ages 18+ years
Condition High-Risk Asthma with T2 Inflammation
Phase Phase 3
Location Plantation, FL

Key Eligibility Criteria

  • Confirmed diagnosis of asthma
  • Evidence of elevated T2 inflammation
  • History of asthma exacerbations despite current therapy
  • Inadequate control on current treatment
  • Non-smoker or former smoker (quit > 6 months ago)
Now Enrolling

NAZARE Study: Uncontrolled Asthma

Evaluating GSK5784283, a TSLP inhibitor with an extended half-life for adults with uncontrolled asthma.

Ages 18+ years
Condition Uncontrolled Asthma
Phase Phase 2/3
Location Plantation, FL

Key Eligibility Criteria

  • Diagnosis of asthma for at least 12 months
  • Uncontrolled asthma despite regular controller medication
  • History of at least 1 asthma exacerbation in the past 12 months
  • On stable dose of medium or high-dose ICS
  • Non-smoker or former smoker with less than 10 pack-years

Previously Conducted Trials

Enrollment Complete

THARROS: COPD & Heart Disease

This study compares BREZTRI vs BEVESPI to determine if optimized COPD treatment can reduce cardiac events like heart attacks and strokes.

Ages 40-80 years
Condition COPD with Cardiovascular Disease
Phase Phase 3
Location Plantation, FL

Key Eligibility Criteria

  • COPD diagnosis with FEV1/FVC ratio < 70%
  • Smoking history ≥ 10 pack-years
  • Blood eosinophil count ≥ 100 cells/mm³
  • CAT score ≥ 10 (phlegm and cough items ≥ 2 each)
  • Cardiovascular disease or risk factors
Enrollment Complete

CALM2: Chronic Cough

Testing camplipixant, a P2X3 inhibitor targeting neuropathic mechanisms for patients with persistent cough lasting more than one year.

Ages 18-80 years
Condition Refractory/Unexplained Chronic Cough
Phase Phase 2
Location Plantation, FL

Key Eligibility Criteria

  • Persistent cough for ≥ 1 year
  • Diagnosis of Refractory/Unexplained Chronic Cough
  • Cough Severity VAS ≥ 40 mm
  • Normal chest imaging within 5 years
  • Non-smoker or former smoker (quit > 6 months ago)
Enrollment Complete

ACT18018: Bronchiectasis

Investigating a novel treatment approach for non-cystic fibrosis bronchiectasis patients who experience frequent pulmonary exacerbations.

Ages 18-85 years
Condition Non-Cystic Fibrosis Bronchiectasis
Phase Phase 3
Location Plantation, FL

Key Eligibility Criteria

  • Confirmed bronchiectasis by CT scan
  • History of chronic cough and sputum production
  • 2+ moderate or 1+ severe exacerbation in past year
  • Non-smoker or former smoker (quit > 6 months ago)
  • No active nontuberculous mycobacteria (NTM) infection
Enrollment Complete

OBERON: COPD Exacerbators

Testing tozorakimab (IL-33 antibody) for patients with COPD who experience frequent exacerbations despite standard therapy.

Ages 40+ years
Condition COPD with Frequent Exacerbations
Phase Phase 2
Location Plantation, FL

Key Eligibility Criteria

  • COPD diagnosis for 1+ year
  • Post-bronchodilator FEV1/FVC < 0.70
  • 2+ moderate or 1+ severe exacerbation in past year
  • On stable dose of maintenance therapy for 3+ months
  • Smoking history ≥ 10 pack-years

Clinical Trial Enrollment Process

Understanding what to expect when you decide to participate in a clinical trial

1

Initial Contact

Contact our research team by phone, email, or through our online form. We'll discuss the basics of the trial and perform a preliminary eligibility assessment.

2

Screening Visit

If potentially eligible, you'll be invited for a screening visit where we'll review your medical history, perform a physical examination, and conduct specific tests to determine if you meet all study criteria.

3

Informed Consent

You'll receive detailed information about the study, including potential risks and benefits. Our team will answer all your questions before you decide whether to participate.

4

Study Participation

If enrolled, you'll receive the study treatment and attend scheduled visits for monitoring and assessments. Our team will provide comprehensive support throughout your participation.

5

Follow-Up Care

After completing the study, you'll have follow-up visits to monitor your health. We'll provide information about continuing care options and any future trials you may be eligible for.

Frequently Asked Questions

Participating in a clinical trial offers several potential benefits:

  • Access to new treatments before they're widely available
  • Comprehensive health assessments and regular monitoring
  • Contributing to medical advancements that may help others
  • All study-related care at no cost to you
  • Compensation for your time and travel expenses

Every trial is different, so specific benefits will be discussed during the informed consent process.

Clinical trials are conducted with patient safety as the top priority. Before any treatment is tested in humans, it undergoes extensive laboratory testing. Additionally:

  • All trials are reviewed and approved by an Independent Ethics Committee
  • Participation is completely voluntary
  • You can withdraw at any time
  • Our team monitors participants closely throughout the study
  • Regular safety reporting ensures any concerns are addressed promptly

While all medical treatments carry some risk, these risks are explained thoroughly during the informed consent process.

This depends on the specific trial. Many studies allow participants to continue their regular medications, while others may require adjustments to certain treatments. During the screening process, our medical team will review all your current medications and discuss any changes that might be necessary for participation. Your health and safety always remain the priority.

The duration varies widely depending on the type of trial. Some studies might last just a few weeks, while others may continue for several months or even years. The time commitment, including the number and frequency of visits, will be clearly explained before you decide to participate. We work to make scheduling as convenient as possible for participants.

Participation in any clinical trial is completely voluntary. You have the right to withdraw at any time, for any reason, without any penalty or loss of benefits to which you're otherwise entitled. If you decide to leave a study, we'll discuss the safest way to discontinue the study treatment and may request a final follow-up visit to ensure your health and safety.

Have more questions? We're here to help.

Contact Our Research Team

Ready to Take the Next Step?

Join our clinical trials to help advance respiratory medicine while gaining access to innovative treatments.